Subjects with both high ALT (> 40 U/L) and high SUA (> 420 μmol/L for man, > 360 μmol/L for woman) levels had a 27-time higher prevalence of NAFLD than subjects with both low ALT and low SUA levels after adjustment for age and sex among all participants, further adjustment of other confounders did not change the association (Table 6). This evidence concerns the gene GPT and metabolic dysfunction-associated steatotic liver disease.