ADPKD is an autosomal dominant inherited disorder resulting from heterozygous mutations in three genes: PKD1, PKD2, and GANAB. Mutations of the first two genes (PKD1 and PKD2) account for 80–85% and 15–20% of resolved cases, respectively [4, 5]. The gene discussed is GANAB; the disease is autosomal dominant polycystic kidney disease.