Moreover, the IBD risk locus RTEL1-TNFRSF6B has recently been fine-mapped to a variant disrupting the transcription factor binding site for EBF1 (Huang et al., 2017), involved in B cell differentiation (Györy et al., 2012), and we subsequently demonstrated the effect on B cell immune phenotype. The gene discussed is EBF1; the disease is inflammatory bowel disease.