After a median time of 43.4 weeks (IQR, 38.0–49.9 weeks) of ART, eight out of 35 (22.9%) persistent CAA-positive patients had HIV RNA concentrations above 1,000 cp/ml, compared to 12 out of 67 (17.9%) of continuously CAA-negative patients after frequency matching for tuberculosis-status, CD4 count, and age. Here, CD4 is linked to tuberculosis.