FOXA1 and head and neck carcinoma: Moreover, the differential expression patterns of FOXA1 indicate that this protein may be important to HPV-associated carcinogenesis: we observed that FOXA1 is expressed at higher levels in immortalized and HPV-transformed cell lines than it is in normal cells 26, and FOXA1 was further shown to be strongly expressed in basal epithelial cells, preinvasive lesions, and cervical and head and neck carcinomas 81.