INS and retinal disorder: As clearly shown in the table, the subgroup of patients treated with insulin also showed longer disease duration (10 ± 9 years vs. 6 ± 7 years, respectively; p < 0.001), higher HbA1c (8.0 ± 1.6% vs. 7.2 ± 1.5%, respectively; p < 0.001), higher triglycerides (both in terms of mean values and of percentage of subjects with values > 150 mg/dl), a greater prevalence of arterial hypertension, and a higher rate of nonproliferative/proliferative retinopathy.