In order to determine PLXNC1 expression levels in HCC, “Chen Liver” microarray dataset (containing 10,802 measured genes through 76 normal and 104 HCC samples) deposited on Oncomine database was analyzed [16]. PLXNC1 mRNA expression was statistically higher (p=3.62e-20) in HCC tissues than in nontumoral adjacent tissues (Figure 1(a)). This evidence concerns the gene PLXNC1 and hepatocellular carcinoma.