TTR and glaucoma: Nevertheless, the intraocular production of TTR V30M by the retinal and ciliary pigment epithelium remains unchanged, contributing to the progression of amyloid deposition-associated ocular manifestations such as abnormal conjunctival vessels, dry eye, scalloped pupils, deposition of amyloid on the anterior surface of the lens and on the pupil border, vitreous amyloidosis, glaucoma, and retinal angiopathy.