In the three cohorts, the majority of patients had cirrhosis (training: 88.0%; internal and external validation: 82.3% and 88.2%, respectively) and slightly higher medium values of gamma-glutamyl transpeptidase (GGT; training: 55 U/L; internal and external validation: 57 and 56.5 U/L, respectively) than normal (50 U/L). Here, GGTLC1 is linked to Cirrhosis.