Notably, SLC26A9 expression was upregulated in Helicobacter pylori infection, as well as upon chronic gastritis induced by interleukin-11 in mice, indicating that SLC26A9 is a key player in gastric mucosal defense under pathological conditions (Henriksnäs et al., 2006; Howlett et al., 2012). The gene discussed is SLC26A9; the disease is chronic gastritis.