CD4 and infection: Considering the increased day 4 CD4+ T and DC cells in infection with 2–4 of the 4 strains and similar day 1 cell counts for uninfected and all infected mice, the observations of inhibited pathways in mice infected with all the parasites such as Th1 pathway, calcium-induced T lymphocyte apoptosis, or role of NFAT in regulation of the immune response are unlikely due to loss of T cell or DC cell populations.