To test whether compromised exosome release alters innervation in vivo, C57Bl/6 mice (n = 7 mice/group) were implanted with mEERL parental or Rab27A−/+Rab27B−/− cells; tumors were harvested and 15 μg of whole tumor lysate quantified by western blot for β-III tubulin, TRPV1 and Tau (Fig. 5b). This evidence concerns the gene TRPV1 and neoplasm.