ABI3 and Alzheimer disease: The African-American control MAF that we observed for these variants were consistent with those reported in the Exome Variant Server [30] (ABI3_rs616338-T = 0.00368; PLCG2_rs72824905-G = 0.00079), which demonstrates lower frequencies compared with Caucasians, suggesting that these particular variants may have a lesser or no role for AD risk in African-Americans.