E2F7 and hepatocellular carcinoma: Similarly, HCC patients with high E2F7 expression and low miRNA-302d levels had significantly decreased OS (P < 0.001) and PFS (P < 0.001) (Fig. 6h), which suggested that E2F7 and miRNA-302a/d might have potential prognostic value and could be useful as tumor biomarkers for the diagnosis of HCC patients.