Our experiments confirmed the hypothesis that AFAP1-AS1 acts as a ceRNA to regulate the expression of key genes, such as LASP1 and RAB11B, by competitively binding miR-423-5p, resulting in dysregulation of the Rho/Rac1 signaling pathway and migration and invasion of human NPC cells [70–72]. Here, LASP1 is linked to nasopharyngeal carcinoma.