To determine the effect of the microvasculature of prostate cancer growing in bone and striated muscle on growth behavior, the prostate cancer cell lines LnCap, Du145, and Pc3 were implanted into the femur [femur window (FW)] and striated muscle [dorsal skinfold chamber (DSC)] of non-obese diabetic/severe combined immunodeficiency/y-chain [NOD-Prkds IL2rg (NSG)] mice. Here, IL2RG is linked to prostate cancer.