The correlation between ERα and CA125 was also significant in the subgroups of G2 and G3 ovarian cancers (p < 0.01; 95% CI 0.1431–0.6367 and p < 0.01; 95% CI 0.0567–0.4210, respectively) (Additional file 2). The gene discussed is MUC16; the disease is ovarian carcinoma.