Moreover, we observed a highly significant correlation between nuclear ERβ and CA72–4 (p < 0.01; 95% CI 0.05953–0.3616) in all ovarian cancer specimens as well as in the serous subtype (p < 0.01; 95% CI 0.08939 to 0.4225). The gene discussed is ESR2; the disease is ovarian carcinoma.