CASP3 and head and neck squamous cell carcinoma: In line with previous findings by Wagner et al. where they have shown the pro-apoptotic potential of YM155 on myeloma cells [50] and head neck squamous cell carcinoma tissues [52], we found that YM155 could elevate the levels of Caspase 3/7 in the LS174T cell line in both the TUN and YM155 alone groups (Figure 10).