FURIN and infection: The dependence of infection on Golgi-resident proteins SPCA1, ERI3 and furin, the pattern of glycosylation of the flavivirus envelope glycoproteins, the importance of low pH environment characteristic of trans-Golgi for the furin-mediated cleavage of the glycoprotein prM and rearrangement of the glycoprotein E on the virion surface, all imply that the virions must transition through a Golgi-like environment on their way to the plasma membrane [92,93,94,95].