The ANGPTL4 p.Glu40Lys variant was associated with protection from coronary disease and diabetes, with effect estimates nearly identical to the ones of triglyceride-lowering alleles in LPL for a given genetic difference in triglyceride levels (Figure 4A) (eFigure 2 in the Supplement). The gene discussed is ANGPTL4; the disease is coronary artery disorder.