In univariate logistic regression analysis, hypertension (OR: 4.85, 95% CI: 2.90–8.08, P < 0.001), history of CVD (OR: 2.16, 95% CI: 1.08–4.29, P = 0.029), intact PTH (OR: 1.01, 95% CI: 1.00–1.01, P < 0.001), plasma NGAL (OR: 1.02, 95% CI: 1.01–1.02, P < 0.001), and the IVCCI < 50% (OR: 12.0, 95% CI: 2.83–50.84, P = 0.001) were the significant predictors of LVDD. This evidence concerns the gene LCN2 and hypertensive disorder.