SOD1 and obesity due to melanocortin 4 receptor deficiency: Obesity was associated with reduced activity of the antioxidant enzyme catalase (170.88 ± 27.46 vs. 317.11 ± 268.98 pmoL / mg in obese and in non - obese patients, respectively; p = 0.01) and with reduced activity of the antioxidant enzyme SOD (0.4 ± 0.19 vs. 0.76 ± 0.59 Usod / mg in obese and in non - obese patients, respectively; p = 0.05).