On the other hand, DNA methylation classification could not reach scores of sufficient confidence for two RELA‐fused ependymomas and misclassified one tumor (#23) as RELA‐fused ependymoma, although this case lacked the fusion and showed no evidence for pathological NFkB activation, and therefore by definition did not qualify for this diagnosis. This evidence concerns the gene NFKB1 and ependymoma.