Therefore, considering the fact that the elevated expression of lncRNA‐MALAT1 in ovarian endometriosis and its connection with autophagy as well as the up‐regulation of both lncRNA‐MALAT1 and autophagy were up‐regulated by hypoxia, we have been suggested that up‐regulation of lncRNA‐MALAT1 by hypoxia may promote autophagy which acts as a cell pro‐survival mechanism in endometriosis. Here, MALAT1 is linked to ovarian endometriosis.