The amount of LC3‐II is correlated with the extent of autophagosome formation, so LC3‐II is widely used for detecting autophagy levels through measuring the ratio of LC3‐ II/Inner control.39 Recent research indicated that up‐regulated autophagy was observed in ovarian endometriomas and this process possibly contributing to the survival of endometriotic cells in ectopic sites and to lesion maintenance.17 In this study, we first proved that the levels of LC3 was elevated in ectopic endometrium tissues of endometriosis. Here, MAP1LC3A is linked to endometriosis.