AKT1 and cancer: Yet, since each of the mTOR and Akt pathways have been implicated in both glioblastoma [9, 15] and neuroblastoma [10, 16], we decided to investigate the efficacy of both drugs in the progression of cancers of nervous origin by studying their effects on two cancer cell lines, namely the glioblastoma U251 and neuroblastoma SH-SY5Y human cell lines.