Using the cut-off of < 31.55% CD38pos MTB-specific CD4 T cells to define LTBI, 37.5% (12 of 32) and 51.4% (18 of 35) of aTB patients had a TAM-TB profile consistent with “LTBI” at W9 and W12 post-treatment, respectively. This evidence concerns the gene CD4 and tuberculosis.