SLU7 and myelodysplastic syndrome: Using correction or introduction of mutations via CRISPR/Cas9 in combination with patient-specific diseased or normal iPSCs, they modeled various disease progression stages ranging from normal/healthy, preleukemic, low-risk MDS, high-risk MDS to MDS/AML (56) as well as the contribution of the splicing factor SRSF2p.P95L mutant to MDS alone or in the context of MDS with del(7q) (40).