ENO2 and brain injury: Our results are in agreement with previous studies that, independent of brain trauma, have observed increases in s100B following aerobic exercise (Stocchero et al., 2014), and increases in s100B and/or NSE after a sporting event (Dietrich et al., 2003; Hasselblatt et al., 2004; Kiechle et al., 2014; Shahim et al., 2015).