ECE1 and infection: To study the influence of Candidalysin on inflammasome activation, we measured IL-1β secretion by LPS-primed primary hMDMs after infection with Wt C. albicans and mutants lacking the entire ECE1 gene (ece1Δ/Δ) or only the Candidalysin-encoding sequence (ece1Δ/Δ + ECE1Δ184–279).