SHQ1 and chronic myelogenous leukemia, BCR-ABL1 positive: To evaluate the role of SHQ1 in different tumor types, we inactivated SHQ1 in B-ALL (RS4;11), acute myeloid leukemia (AML) (HL-60), chronic myeloid leukemia (CML) (K562), and lung cancer (A549) cell lines.