Specifically, quantification of triple immunofluorescence staining of eight BO EMR specimens with intestinal metaplasia but no dysplasia taken from five patients showed 41% of MUC2 low cells expressed SPINK4 and/or ITLN1, whereas 28% of cells expressed MUC2 alone (Supplementary Table 3). This evidence concerns the gene ITLN1 and bronchiolitis obliterans syndrome.