DCT and melanoma: Since the peak time for melanogenesis-related genes expression upon SCF and α-MSH stimulation is known for human G361 (Figure 2) and mouse B16F10 melanoma cells [4], respectively, we further measured the expression of MITF, tyrosinase, TYRP1, and TYRP2 in ZER treated mouse B16F10 melanoma cells after 2 h or 48 h of incubation with α-MSH.