By suppressing several targets involved in BCR signaling, such as growth arrest and DNA damage inducible alpha (GADD45A), phosphatase and tensin homolog (PTEN) and BCL2 like 11 (BCL2L11), upregulation of miR-148a promotes survival of immature B cells in a lupus mouse model [74]. The gene discussed is PTEN; the disease is systemic lupus erythematosus.