Among the 30 genes selected, four were previously identified using functional genomic screening in Drosophila as modifiers of tauopathy: Mark1, Camk1, Ercc4 (50) and Nab1 (51) and three were previously identified during microarray assays as deregulated in KOTau versus WT primary neuronal cultures (MC Galas, unpublished results): Cbfa2t2, Cnot4, Tnrc6b. The gene discussed is CNOT4; the disease is tauopathy.