In univariate analysis, duration of hospitalisation, seizures, disseminated disease (shock, ARDS, pulmonary haemorrhage), tachypnoea, hepatomegaly, neutrophil (%) count, albumin, low platelet count and HAdV type 7 (compared to the other types) were significantly associated with development of severe disease. The gene discussed is ALB; the disease is Pulmonary hemorrhage.