SNCA and Parkinsonism: We found that SNCA is expressed at higher levels in granule neurons relative to basket neurons (Figure 4—figure supplement 1E); correspondingly, we identified seven regions around the SNCA gene that are preferentially accessible in granule neurons (Figure 4—figure supplement 1E) and may regulate SNCA expression in cis. These putative regulatory regions contain two SNPs that have previously been linked to Parkinson's - rs356182 and rs2736990.