RALA and neoplasm: Moreover, Ral-GTP level were found elevated in various tumor-derived cell lines harboring different Ras status, including pancreas (Lim et al., 2005), colon (Martin et al., 2011), bladder (Saito et al., 2013), liver (Ezzeldin et al., 2014), lung (Male et al., 2012) and brain (Ginn et al., 2016).