INS and Hyperglycemia: Previous studies had found that pharmacologically relevant FGF1 doses (0.5 mg/kg) to T2D mouse models (ie, ob/ob or db/db) with impaired insulin sensitivity led to impressive changes in several measures of metabolism in which blood glucose was nearly normalized and long‐lasting (35 days).37 Our results expanded on this notion by showing that FGF1 blocked the hyperglycemia in db/db mice.