MAPK8 and diabetes mellitus: Nuclear factor (erythroid‐derived 2)‐like 2 (Nrf2) is a transcription factor that controls redox balance through regulating expression of many antioxidant and anti‐inflammatory genes.2 It has been reported that JNK inactivation can significantly activate Nrf2 and subsequently attenuate diabetes‐induced inflammation, fibrosis, and oxidative stress.3 Furthermore, JNK2 deficiency can protect the liver from oxidative injury induced by haemorrhage and resuscitation.4