Bleomycin-induced model: 1. Aggravated lung fibrosis (as assessed by histologic analysis, hydroxyproline levels, and survival rate) in CD1d-deficient and Jα18−/− mice 2. Reversal of fibrosis upon adoptive transfer of iNKT cells to CD1d-deficient mice 3. IFN-γ-producing iNKT cells secrete TGF-β, which contributes to fibrotic changes. The gene discussed is IFNG; the disease is pulmonary fibrosis.