Sphingomonas glycolipid challenge: 1. Asthmatic phenotype (AHR, eosinophilia, histology, type 2 cytokine (IL-4 and IL-13) production, and increased serum IgG) induced only by α-GalCer or Sphingomonas glycolipid 2. No effect on AHR in MHC II-deficient mice. This evidence concerns the gene IL13 and Increased total eosinophil count.