Similar findings, such as the fact that HLA-G and paired immunoglobulin-like receptor B (PIR-B, murine homolog of human ILT receptors) engagement expanded the population of CD11b+Gr1+PIR-B+ MDSCs in an M8-HLA-G1 (human melanoma cell line) tumor-bearing mouse model, have also been reported (32). Here, ITGAM is linked to neoplasm.