IL13 and allergic disease: However, additional adjuvants that modify mast cell immunity, enhance Th1 and/or T regulatory cell responses, including interferon (IFN)-γ and/or interleukin (IL)-10, respectively or utilize host machinery to down-regulate pro-allergy phenotypes, including Th2-associated IL-4, IL-5, and IL-13, may be beneficial for treating peanut allergy.