Cases of renal dysfunction were more prevalent among patients with the ERCC1 gene rs11615 heterozygous T/C (46.7%) with OR = 2.51 (95% CI 1.09–5.57; p = 0.037) and rs3212986 heterozygous C/A (52.8%) genotypes with OR = 3.29 (95% CI 1.40–7.73; p = 0.009) compared with the homozygous variants. The gene discussed is ERCC1; the disease is Abnormal renal physiology.