BCL2 and acute myeloid leukemia: Beyond this, b-AP15 can also effectively inhibit the dissemination of acute myeloid leukemia (AML) mouse model of C1498 leukemia, and inhibit the carcinogenesis process in multiple solid tumor mouse models, including Lewis lung carcinomas (LLCs) xenografts, HCT-116 colon carcinoma xenografts overexpressing BCL2, 4T1 breast carcinomas xenografts, etc. (D'Arcy et al., 2011; Pal et al., 2014; Tian et al., 2014).