TARDBP and amyotrophic lateral sclerosis: Executive function, memory and disinhibited behavior were selected for cognitive staging criteria, since these cognitive functions are attributed to cerebral areas analogous to the pattern of MRI markers of TDP-43 pathology, showing that cognitive impairment follows specific patterns in ALS and, in analogy to DTI-based staging, these patterns are useful to set up a cognitive staging (Lulé et al., 2018).