MTOR and obesity due to melanocortin 4 receptor deficiency: In our recent publication, “Adipocyte-specific double knockout of Lkb1 and mTOR protects mice against high-fat diet induced obesity but results in insulin resistance”, published in Journal of Lipid Research, we generated adipocyte-specific Lkb1 and mTOR double knockout (DKO) mice and assessed how genetic knockout of both Lkb1 and mTOR affects adipose tissue development and function in energy homeostasis 5.