VASH2 and pachyonychia congenita: It can also stimulate the EMT by activating two main proteins of the EMT pathways, Akt and NF‐kB.22, 23, 24 The finding that VASH2 can significantly increase the proportion of CD44+ cells suggest that VASH2 may promote the metastasis of PC by increasing the proportion of cancer stem cell‐like cells in PC cells.