CAT and B-cell chronic lymphocytic leukemia: As we recently published that low expression of the antioxidant gene catalase confers redox hypersensitivity in CLL patients,48 we here investigated the involvement of mutant p53 in the redox regulation of CLL and we find a correlation between the poor clinical outcome of CLL patients having mutant TP53 gene with a decreased amount of intracellular reduced thiols.