For those cases with available data at the time of grade 3 anaemia, we observed a wide range of haemolysis parameters, including bilirubin (0.4–2.0 mg/dL), LDH (165–560 units/L), haptoglobin (155–408 mg/dL), and reticulocytes (2.9–8.6%). Here, HP is linked to anemia (phenotype).