•Although recurrent Hypercalcemia with high serum PTH level, jaw tumor, and bilateral parathyroid adenomas in99mTc-MIBI parathyroid scintigraphy suggesting HPT-JT, her old age, lack of similar familial history, absence of nonendocrine malignancy as well as evidence of malignancy in the patient's parathyroid pathology, this diagnosis was not supported. The gene discussed is PTH; the disease is hypercalcemia disease.